Citamos aquí algunas publicaciones científicas sobre investigaciones sobre Proloterapia.
  • MJ Ongley, RG Klein, TA Dorman, BC Eek and LJ Hubert A new approach to the treatment of chronic low back pain The Lancet July 18 143-146 (1987)

  • RC Klein, TA Dorman and CE Johnson Proliferant injections for low back pain: histologic changes of injected ligaments and objective measurements of lumbar spine mobility before and after treatment J of Neurol and Ortho Med and Surg 10:2 123-126

  • Hackett, George A., and Henderson, Donald G., "Joint Stabilization: An Experimental, Histologic Study with Comments on the Clinical Application in Ligament Proliferation", American Journal of Surgery, 89 (May 1955), pp. 968-973.

  • Klein, Robert G., "Proliferant Injections for Low Back Pain: Histologic Changes of Injected Ligaments and Objective Measures of Lumbar Spine Mobility Before and After Treatment," Journal of Neurology, Orthopedic Medicine and Surgery, 1989, 10:141-144.

  • Klein, Robert G., Mooney, Vert, et al,"A Randomized Double-Blind Trial of Dextrose-Glycerine-Phenol Injections for Chronic Low Back Pain", Journal of Spinal Disorders, 1993, 6:23-33.

  • Lui, Y. King, et al, "An In Situ Study of the Influence of a Sclerosing Solution in Rabbit Medial Collateral Ligaments and Its Junction Strength", Connective Tissue Research, 11 (1983), pp. 95-102.

  • Dorman, Thomas A., editor, Prolotherapy in the Lumbar Spine and Pelvis, Spine: State of the Art Reviews, Volume 9, Number 2, Philadelphia, Hanley and Belfus, Inc, 1995.

  • Reeves, K. Dean, "Technique of Prolotherapy", Physiatric Procedures, Lennard, Ted A., editor, pp.57-70, Philadelphia, Hanley and Belfus, 1995.

  • Reeves KD Hassanein KM Long term effects of dextrose prolotherapy for anterior cruciate ligament laxity: A prospective and consecutive patient study. Alt Ther Hlth Med (United States), May_Jun 2003, 9(3) p58-62.

  • Sonographically Guided Intratendinous Injection of Hyperosmolar Dextrose to Treat Chronic Tendinosis of the Achilles Tendon: A Pilot Study Norman J. Maxwell1,2 AJR 2007; 189:W215 W220

    Topol GA, Reeves KD, Hassanein K. Efficacy of Dextrose Prolotherapy in Elite Male Kicking-Sport Athletes With Chronic Groin Pain. Archives PM&R.

    Arch Phys Med Rehabil Vol 86, April 2005



Dr. Gastón  Andrés Topol
Médico Especialista en Medicina Física y Rehabilitación
Presidente de la Asociación Latinoamericana de Medicina Ortopédica |


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